Do individuals who are sexually abstinent require a Papanicolaou (Pap) smear?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 9, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Virgins do not need to start Pap smears until they are 21 years old, regardless of their sexual activity status, as recommended by the American Cancer Society and other health organizations. This guideline is based on the evidence that cervical cancer incidence and mortality rates have declined significantly since the introduction of the Papanicolaou (Pap) smear, and that screening should begin at age 21 years 1. The recommendation to start screening at 21 is not dependent on the age of sexual initiation, and women younger than 21 years should not be screened.

Some key points to consider for virgins and Pap smears include:

  • Women ages 21 to 29 years should receive cytology screening every 3 years with either conventional cervical cytology smears or liquid-based cytology 1.
  • Human papillomavirus (HPV) testing should not be used for screening women in this age group, although it can be used as a reflex test for women diagnosed with atypical squamous cells of undetermined significance (ASC-US) 1.
  • For women ages 30 to 65 years, the preferred approach is cotesting every 5 years with cytology and HPV testing, or screening every 3 years with cytology alone 1.
  • Women should discontinue screening after age 65 years if they have had 3 consecutive negative cytology tests or 2 consecutive negative cotest results within the 10-year period before ceasing screening 1.

It's essential to follow these guidelines to ensure that virgins receive appropriate cervical cancer screening, as other risk factors for cervical cancer exist, and abnormal cell changes can occur even without sexual activity. Regular screenings are crucial for early detection of cervical abnormalities, allowing for more effective treatment if issues are found.

From the Research

Cervical Cancer Screening for Virgins

  • The provided studies do not directly address whether virgins need pap smears, but they do discuss cervical cancer screening guidelines and risk factors 2, 3, 4.
  • According to the studies, cervical cancer screening is generally recommended for women who are sexually active, as the primary risk factor for cervical cancer is human papillomavirus (HPV) infection, which is usually transmitted through sexual contact 3, 4.
  • However, the studies also note that HPV vaccination is recommended for all individuals, regardless of sexual activity, to prevent HPV infection and reduce the risk of cervical cancer 4.
  • The American Society for Colposcopy and Cervical Pathology (ASCCP) guidelines recommend that primary care clinicians offer HPV vaccination to all patients between the ages of nine and 26, in addition to cervical cancer screening and follow-up guidance 4.
  • It is essential to consider individual risk factors, such as HPV vaccination status and sexual history, when determining the need for cervical cancer screening 2, 3, 4.

Risk Factors and Screening Guidelines

  • The studies emphasize the importance of considering patient risk factors, such as HPV subtype, persistence of HPV infection, and cytology results, when determining the need for colposcopy or other diagnostic procedures 4.
  • The ASCCP guidelines recommend shared decision-making between clinicians and patients regarding immediate loop electrosurgical excision procedure vs. colposcopy with multiple biopsies and endocervical sampling for patients with high-risk HPV subtypes or abnormal cytology results 4.
  • Long-term surveillance is recommended for patients with a history of cervical dysplasia or cervical cancer 4.
  • The studies suggest that cervical cancer screening guidelines may vary depending on individual risk factors, age, and HPV vaccination status 2, 3, 4.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.