From the Research
Definition and Diagnosis of Aortic Regurgitation
- Aortic regurgitation (AR) is a common form of valvular disease characterized by reflux of blood from the aorta into the left ventricle (LV) during diastole 1.
- The clinical presentation of patients with AR depends on the severity of the regurgitation and differs whether AR develops acutely or if it progresses over a prolonged period, allowing the cardiac chambers to adapt 1, 2.
- Echocardiography is the primary method to determine the etiology of AR and to define its severity 1.
Physical Signs and Eponyms
- Aortic regurgitation is associated with numerous eponymous signs, including pulsatile pseudo-proptosis 3.
- The presence of an early diastolic murmur is a useful finding for ruling in AR, with a positive likelihood ratio of 8.8-32.0 4.
- The absence of an early diastolic murmur is a useful finding for ruling out AR, with a negative likelihood ratio of 0.2-0.3 4.