From the Research
For diverticulitis, Augmentin (amoxicillin-clavulanate) is typically prescribed at a dose of 875 mg/125 mg taken orally twice daily for 7-10 days, as supported by the most recent and highest quality study 1. This dose provides broad-spectrum coverage against both aerobic and anaerobic bacteria commonly found in the intestinal flora that can cause infection when diverticula become inflamed. Some key points to consider when prescribing Augmentin for diverticulitis include:
- It's essential to take the full course of antibiotics even if symptoms improve before completion.
- Augmentin should be taken with food to reduce stomach upset.
- Common side effects include diarrhea, nausea, and skin rash.
- If you have a penicillin allergy, Augmentin would not be appropriate, and alternative antibiotics like a fluoroquinolone plus metronidazole would be considered instead, as noted in 2 and 1.
- Adequate hydration and a temporary liquid or low-fiber diet are also typically recommended during acute diverticulitis treatment alongside antibiotics, as discussed in 3. The choice of antibiotic and treatment strategy may depend on the severity of the diverticulitis, patient factors, and disease characteristics, as outlined in 4 and 5. However, based on the most recent evidence 1, amoxicillin-clavulanate is a suitable option for outpatient treatment of uncomplicated diverticulitis, with a dose of 875 mg/125 mg taken orally twice daily for 7-10 days.