What are the best laboratory tests for diagnosing dizziness (vertigo)?

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From the Guidelines

The best initial laboratory tests for evaluating dizziness include a complete blood count (CBC), comprehensive metabolic panel (CMP), thyroid function tests (TSH, T3, T4), hemoglobin A1C, vitamin B12 and folate levels, and electrolytes (particularly potassium, sodium, and calcium) 1. These tests help identify common causes of dizziness such as anemia, electrolyte imbalances, diabetes, thyroid dysfunction, and nutritional deficiencies. Additional specialized tests may be considered based on the patient's symptoms and physical examination findings, such as:

  • Vestibular function tests like electronystagmography (ENG) or videonystagmography (VNG) to assess inner ear function
  • Audiometry to evaluate hearing
  • Brain imaging studies such as MRI if a central nervous system cause is suspected
  • Blood pressure measurements in different positions (lying, sitting, standing) to check for orthostatic hypotension It is essential to note that radiographic imaging, such as CT or MRI, is not recommended for patients with suspected benign paroxysmal positional vertigo (BPPV) unless there are additional signs or symptoms that warrant imaging 1. Similarly, vestibular function testing is not recommended for patients who meet diagnostic criteria for BPPV without additional vestibular signs or symptoms 1. The specific combination of tests ordered should be tailored to the patient's symptoms, medical history, and physical examination findings, and should prioritize the most recent and highest quality evidence available 1.

From the Research

Diagnostic Approach

The diagnostic approach for dizziness involves a thorough evaluation of the patient's symptoms, medical history, and physical examination. The following steps can be taken:

  • Identify the timing and triggers of dizziness to develop a differential diagnosis 2, 3, 4
  • Perform a physical examination, including orthostatic blood pressure measurement, a full cardiac and neurologic examination, assessment for nystagmus, and the Dix-Hallpike maneuver 2, 3
  • Use the HINTS (head-impulse, nystagmus, test of skew) examination to distinguish peripheral from central etiologies 2, 3

Laboratory Testing and Imaging

Laboratory testing and imaging are not always required and are usually not helpful in diagnosing dizziness 2, 5, 3. However, they may be ordered if the patient has abnormal findings on physical examination that may indicate a more serious cause of dizziness 6.

Treatment

The treatment for dizziness depends on the underlying cause. The following treatments may be effective:

  • Canalith repositioning procedures (e.g., Epley maneuver) for benign paroxysmal positional vertigo 2, 3
  • Vestibular rehabilitation for peripheral and central etiologies 2
  • Pharmacologic intervention, although limited, may be used to treat specific causes of dizziness 2
  • Salt restriction and diuretics for Meniere disease 3
  • Vestibular suppressant medications and vestibular rehabilitation for vestibular neuritis 3

Common Causes of Dizziness

The most common causes of dizziness include:

  • Peripheral vestibulopathies (35% to 55% of patients) 5
  • Psychiatric disorders (10% to 25% of patients) 5
  • Benign paroxysmal positional vertigo 6
  • Orthostatic hypotension 6
  • Vestibular neuritis 3
  • Meniere disease 3

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Dizziness: Evaluation and Management.

American family physician, 2023

Research

Dizziness: Approach to Evaluation and Management.

American family physician, 2017

Research

A New Diagnostic Approach to the Adult Patient with Acute Dizziness.

The Journal of emergency medicine, 2018

Research

Evaluating dizziness.

The American journal of medicine, 1999

Research

Office evaluation of dizziness.

Primary care, 2015

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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