What is the differential diagnosis for ecchymosis (bruising) of the breast?

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Last updated: May 10, 2025 • View editorial policy

Differential Diagnosis for Bruising to the Breast

Single Most Likely Diagnosis

  • Trauma: This is the most likely diagnosis, as bruising to the breast is often caused by direct trauma, such as a fall or a blow to the chest. The location and appearance of the bruise can provide clues about the mechanism of injury.

Other Likely Diagnoses

  • Surgical or procedural complication: Bruising can occur after breast surgery, biopsies, or other medical procedures. The history of recent medical intervention can help support this diagnosis.
  • Hematoma: A collection of blood outside of blood vessels, which can occur spontaneously or as a result of trauma. A hematoma can cause bruising and swelling in the breast tissue.
  • Insect bite or sting: Certain insect bites or stings can cause bruising, especially if there is an allergic reaction.

Do Not Miss Diagnoses

  • Breast cancer: While rare, breast cancer can cause bruising, especially if there is a tumor that is bleeding or if cancer has invaded the skin. A new bruise or unexplained bruising in the breast should prompt further evaluation.
  • Inflammatory breast cancer: This aggressive type of breast cancer can cause skin changes, including bruising, redness, and swelling.
  • Warfarin or anticoagulant use: Patients taking anticoagulant medications are at increased risk of bruising, including in the breast tissue.

Rare Diagnoses

  • Fat necrosis: A rare condition in which the fatty tissue in the breast becomes damaged, leading to bruising, swelling, and sometimes a palpable mass.
  • Mondor's disease: A rare condition characterized by thrombophlebitis of the superficial veins of the breast, which can cause bruising, swelling, and pain.
  • Amyloidosis: A rare condition in which abnormal proteins accumulate in the body, including in the breast tissue, which can cause bruising and other symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.