What is the treatment for dyshidrotic (dyshidrotic) eczema?

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From the Research

Treatment for dyshidrotic eczema typically involves a combination of self-care measures and medications, with dupilumab being a promising option for severe cases, as reported in a 2018 study 1. When managing dyshidrotic eczema, it's essential to avoid triggers such as irritants, allergens, and excessive moisture. Keeping the affected areas clean and dry, and applying moisturizers regularly to maintain skin hydration is crucial.

  • For mild cases, over-the-counter topical corticosteroids like hydrocortisone 1% cream can be applied twice daily for 1-2 weeks.
  • For moderate to severe cases, prescription-strength topical corticosteroids such as betamethasone dipropionate 0.05% ointment may be needed, applied twice daily for 2-4 weeks, as guided by the fingertip unit method 2.
  • Calcineurin inhibitors like tacrolimus 0.1% ointment or pimecrolimus 1% cream are steroid-free alternatives, especially useful for sensitive areas.
  • Oral antihistamines such as cetirizine 10mg daily can help manage itching.
  • For severe or resistant cases, oral corticosteroids like prednisone (starting at 20-40mg daily with a tapering schedule) may be prescribed for short periods, or phototherapy (UVB light) treatments 2-3 times weekly for 6-8 weeks might be recommended.
  • Severe chronic cases might require immunosuppressants like methotrexate or cyclosporine, or biologics like dupilumab, which has shown efficacy in treating dyshidrotic eczema 1. During flares, cold compresses can provide immediate relief, and soaking affected areas in cool water with colloidal oatmeal may soothe the skin. It's also important to note that the use of topical corticosteroids, such as clobetasol propionate, should be limited to a maximum of 2 weeks to minimize the risk of side effects 3.

References

Research

Dupilumab in the Treatment of Dyshidrosis: A Report of Two Cases.

Journal of drugs in dermatology : JDD, 2018

Research

Topical Corticosteroids: Choice and Application.

American family physician, 2021

Research

Impetiginized Dyshidrotic Eczema.

Open access Macedonian journal of medical sciences, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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