From the Research
To treat a sandpaper rash, apply an over-the-counter hydrocortisone cream (0.5-1%) 2-3 times daily for up to 7 days to reduce inflammation and itching, as recommended by the most recent and highest quality study 1. When treating a sandpaper rash, it is essential to prioritize reducing inflammation and itching.
- Clean the affected area gently with mild soap and lukewarm water.
- Apply hydrocortisone cream (0.5-1%) 2-3 times daily for up to 7 days.
- For additional relief, take an oral antihistamine like diphenhydramine (Benadryl) 25-50mg every 6 hours as needed, as suggested by previous studies 2, 3.
- Keep the area clean, dry, and avoid further irritation by wearing loose clothing.
- Apply a fragrance-free moisturizer like Cetaphil or CeraVe after the hydrocortisone has absorbed to maintain skin barrier function. This treatment approach is supported by the study on topical corticosteroids 1, which highlights their effectiveness in treating inflammatory skin conditions. If the rash doesn't improve within a week, shows signs of infection (increasing redness, warmth, pus, or streaking), or is accompanied by fever or severe pain, seek medical attention as you may need prescription-strength treatments or antibiotics, as noted in the study on treatment of eczema 3.