Is Augmentin (amoxicillin-clavulanate) indicated for treatment of a cat bite?

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Last updated: May 11, 2025View editorial policy

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From the Guidelines

Augmentin (amoxicillin-clavulanate) is the recommended first-line antibiotic for cat bite infections, with a typical adult dose of 875/125 mg taken orally twice daily. The treatment duration is usually 5-7 days, but may extend to 10-14 days for deeper or more severe infections 1. Cat bites often cause deep puncture wounds that introduce bacteria, particularly Pasteurella multocida, which can cause rapid infection development within 24-48 hours. Augmentin is effective because it combines amoxicillin with clavulanic acid, which helps overcome bacterial resistance by inhibiting beta-lactamase enzymes.

Some key points to consider when treating cat bite infections include:

  • Prompt antibiotic treatment is essential to prevent infection development
  • Thorough wound cleaning with soap and water is crucial
  • Medical attention should be sought promptly, especially for bites on hands, joints, or face
  • People with compromised immune systems, diabetes, or liver disease may need special consideration
  • Signs of worsening infection, such as increasing redness, swelling, warmth, pus, fever, or red streaking from the wound, require immediate medical attention 1.

It's also important to note that Augmentin may not be effective against all types of bacteria, such as MRSA, and alternative antibiotics may be necessary in some cases 1. However, based on the current evidence, Augmentin remains the recommended first-line treatment for cat bite infections.

From the Research

Augmentin for Cat Bites

  • Augmentin, also known as amoxicillin/clavulanate, is recommended for the prophylactic treatment of cat bites due to the high risk of infection 2, 3.
  • Cat bites can become infected with bacteria such as Pasteurella multocida, which can cause serious complications 3.
  • The use of amoxicillin/clavulanate as a first-line prophylactic antibiotic is suggested, especially for high-risk wounds such as cat bites, puncture wounds, and wounds to the hand 2.
  • It is also important to consider the need for rabies prophylaxis and tetanus immunization status when managing cat bite wounds 2, 3.
  • Proper wound care, including cleaning and irrigation with normal saline, is also essential in preventing infection 2.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Dog and cat bites.

American family physician, 2014

Research

Management of cat and dog bites.

American family physician, 1995

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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