Moxifloxacin 0.5% Eye Drops Dispensing
Moxifloxacin 0.5% ophthalmic solution is dispensed as a sterile solution in a 3 mL fill volume contained within a 5 mL natural low-density polyethylene (LDPE) bottle with an integrated dropper nozzle and sealed cap 1.
Packaging Specifications
The standard commercial packaging consists of:
- Bottle material: Natural low-density polyethylene (LDPE)
- Bottle size: 5 mL capacity
- Fill volume: 3 mL of solution
- Dropper: Integrated natural LDPE nozzle for direct drop instillation
- Cap: Tan-colored high-density polyethylene (HDPE) seal
- NDC code: 80425-0379-01 1
Storage Requirements
The product must be stored at 2°C to 25°C (36°F to 77°F) 1. This relatively broad temperature range allows for both refrigerated and room temperature storage, providing flexibility for pharmacy and patient storage conditions.
Formulation Details
Each mL contains 5.45 mg moxifloxacin hydrochloride (equivalent to 5 mg moxifloxacin base), creating a 0.5% concentration 1. The solution is:
- Self-preserved (no separate preservative needed)
- Near-neutral pH of approximately 6.8
- Isotonic with osmolality of approximately 290 mOsm/kg
- Yellow-colored transparent solution 1
Clinical Context
The self-contained dropper bottle design allows patients to directly instill drops without additional equipment. The 3 mL volume provides sufficient medication for typical treatment courses of bacterial conjunctivitis (twice-daily dosing for 3 days) 2 or perioperative prophylaxis regimens, while the smaller fill volume in a larger bottle facilitates easier handling and drop formation.