What is the cause of weight loss with Monjaro (likely referring to a dietary regimen or a specific condition, but assuming it's related to a medication, it could be Monjuvi, however without further context, the exact medication is unclear)?

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From the FDA Drug Label

The FDA drug label does not answer the question.

From the Research

Mounjaro (tirzepatide) is a highly effective medication for weight loss, and when combined with a reduced-calorie diet and regular physical activity, it can lead to significant weight loss, typically 15-20% of body weight over 12-18 months, as supported by the most recent and highest quality study 1. The medication works by mimicking two hormones (GLP-1 and GIP) that regulate blood sugar and appetite, helping you feel fuller longer and reducing food cravings. Some key points to consider when using Mounjaro for weight loss include:

  • Starting with a low dose of 2.5 mg weekly and gradually increasing to a maximum of 15 mg weekly as tolerated
  • Combining Mounjaro with a reduced-calorie diet and regular physical activity for best results
  • Monitoring for common side effects such as nausea, vomiting, diarrhea, and constipation, which often improve over time
  • Regular follow-up appointments with a healthcare provider to monitor progress and manage any side effects It's also important to note that Mounjaro requires a prescription and should be used under medical supervision, as it's not appropriate for everyone, particularly those with certain medical conditions like medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2, as highlighted in the study 1. Additionally, a comprehensive approach to weight loss, including reduced dietary intake, regular physical activity, and behavioral strategies, is warranted and supported by research evidence, as discussed in the study 2. Overall, Mounjaro is a valuable treatment option for weight loss, and when used in conjunction with a healthy lifestyle, it can lead to significant and sustainable weight loss, as supported by the study 1.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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