What is the most likely diagnosis of a cystic neck mass with a sinus tract leaking mucopurulent fluid in a 12-year-old boy, following a recent upper respiratory tract infection (URTI)?

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Differential Diagnosis for a 12-year-old boy with a left neck mass

  • Single most likely diagnosis
    • B. Branchial cleft cyst: This is the most likely diagnosis due to the presence of a cystic neck mass, a small pit anterior to the sternocleidomastoid muscle, and leakage of mucopurulent fluid. The history of a recent upper respiratory tract infection and the development of a painful lump in the neck also supports this diagnosis, as branchial cleft cysts can become infected and present with these symptoms.
  • Other Likely diagnoses
    • A. Actinomyces lymphadenitis: This is a possible diagnosis, given the patient's history of a recent infection and the presence of a neck mass with mucopurulent drainage. Actinomyces infections can cause abscesses and sinus tracts, which could explain the leakage of fluid from the pit.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Tuberculous lymphadenitis: Although not listed among the options, tuberculous lymphadenitis is a critical diagnosis to consider in a patient with a neck mass and a history of infection. It can present with similar symptoms, including a painful mass and drainage, and is a potentially life-threatening condition if left untreated.
    • Malignancy (e.g., lymphoma): Although less likely, malignancy is always a concern in a patient with a persistent neck mass, especially if there are systemic symptoms such as fever or weight loss.
  • Rare diagnoses
    • C. Cystic hygroma: This is a congenital anomaly that typically presents at birth or in early childhood, making it less likely in a 12-year-old boy.
    • D. Laryngocele: This is a rare condition that typically presents with a neck mass and respiratory symptoms, such as stridor or dyspnea, which are not mentioned in the case.
    • E. Thyroglossal duct cyst: This is a congenital anomaly that typically presents as a midline neck mass, which does not match the patient's presentation of a left-sided mass.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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