Differential Diagnosis for Sole and Palm Itching
- Single most likely diagnosis
- Dry skin (xerosis): This is a common condition that can cause itching on the soles and palms due to lack of moisture, especially in dry environments or during winter months.
- Other Likely diagnoses
- Eczema (atopic dermatitis): A chronic skin condition characterized by itchy, inflamed skin, which can affect the palms and soles.
- Psoriasis: An autoimmune condition that can cause red, scaly, and itchy patches on the skin, including the palms and soles.
- Contact dermatitis: A type of skin inflammation caused by contact with irritants or allergens, which can lead to itching on the palms and soles.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Liver disease (e.g., primary biliary cirrhosis): Severe itching can be a symptom of liver disease, and it's essential to rule out this possibility due to its potential severity.
- Thyroid disorders (e.g., hyperthyroidism): Some thyroid conditions can cause itching, and missing this diagnosis could lead to delayed treatment and complications.
- Lymphoma: Certain types of lymphoma can cause itching, and early detection is crucial for effective treatment.
- Rare diagnoses
- Aquagenic pruritus: A rare condition characterized by itching after exposure to water, which can affect the palms and soles.
- Polycythemia vera: A rare blood disorder that can cause itching, especially after exposure to water.
- Cholestasis: A condition characterized by reduced bile flow, which can cause severe itching, including on the palms and soles.