Can Morton’s neuroma cause the toes to spread apart?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 8, 2026 • View editorial policy

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.

Morton's Neuroma Does Not Cause Toes to Spread Apart

Morton's neuroma does not cause the toes to spread apart. In fact, the opposite may be observed on imaging—when visible on radiographs, splaying of the metatarsals or soft-tissue density may be demonstrated, but this is not diagnostic and represents a radiographic finding rather than a clinical presentation 1.

Understanding the Pathology

Morton's neuroma is a benign perineural fibrosis of the common plantar digital nerve, typically occurring in the third intermetatarsal space (the webspace between the third and fourth toes) 2, 3. The condition results from:

  • Entrapment or repeated microtrauma to the nerve
  • Compression of the nerve between metatarsal heads
  • Secondary fibrotic changes rather than a true neuroma

Clinical Presentation

Patients with Morton's neuroma present with characteristic symptoms that do not include toe spreading:

  • Burning or shooting pain in the webspace that extends to the toes (sensitivity 54-57%) 4
  • Sensation of "walking on a pebble" (sensitivity 43-53%) 4
  • Subjective clicking reported by the patient (highly specific at 96%, positive likelihood ratio 13.14) 4
  • Pain exacerbated by tight, high-heeled shoes 5
  • Paroxysmal neuralgia so severe patients become anxious about weight-bearing 6

Key Diagnostic Features

The modified webspace tenderness test (thumb-index finger squeeze test) is highly sensitive (96%) with a low negative likelihood ratio (0.04), making it excellent for ruling out Morton's neuroma when negative 4.

Important Caveat

If you observe actual toe spreading or splaying in a patient, consider alternative diagnoses such as:

  • Plantar plate tears (which can cause toe deviation and spreading)
  • Metatarsophalangeal joint arthritis
  • Interdigital bursitis
  • Hallux valgus deformity

These conditions can be differentiated using MRI, which has 93% sensitivity and 68% specificity for Morton's neuroma 1, and can also identify plantar plate pathology with 95% sensitivity 1.

References

Guideline

acr appropriateness criteria® chronic foot pain.

Journal of the American College of Radiology, 2020

Research

[Morton's disease].

Brain and nerve = Shinkei kenkyu no shinpo, 2014

Research

Interventions for the treatment of Morton's neuroma.

The Cochrane database of systematic reviews, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.