What is the diagnosis for a 27-year-old female presenting with constant right flank pain, Costovertebral angle (CVA) tenderness, right lower quadrant (RLQ) pain with palpation, rebound tenderness, trace hematuria, and leukocyturia?

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Differential Diagnosis for 27-year-old Female with Right Flank Pain

Single most likely diagnosis

  • Pyelonephritis or Kidney Infection: The patient's symptoms of constant right flank pain, costovertebral angle (CVA) tenderness, and the presence of leukocytes and trace blood in the urine are highly suggestive of a kidney infection. The pain in the right lower quadrant (RLQ) with palpation and rebound tenderness may indicate involvement or irritation of the surrounding tissues.

Other Likely diagnoses

  • Nephrolithiasis (Kidney Stones): The patient's history of intermittent flank pain and the presence of trace blood in the urine could be indicative of kidney stones, which are a common cause of flank pain.
  • Appendicitis: Although the pain is primarily in the flank, the presence of RLQ pain and rebound tenderness could suggest appendicitis, especially if the appendix is retrocecal.
  • Ovarian Cyst or Torsion: The patient's sex and the location of the pain could suggest an ovarian pathology, such as a cyst or torsion, which can cause severe pain and tenderness.

Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)

  • Ectopic Pregnancy: Although the patient's symptoms do not strongly suggest pregnancy, it is crucial to consider ectopic pregnancy in any female of childbearing age presenting with abdominal pain, as it is a life-threatening condition.
  • Ruptured Aneurysm or Aortic Dissection: These vascular emergencies can present with severe flank or abdominal pain and are life-threatening if not promptly diagnosed and treated.
  • Sepsis: The presence of leukocytes and trace blood in the urine could indicate a severe infection, and sepsis should be considered, especially if the patient shows signs of systemic illness.

Rare diagnoses

  • Renal Infarction: This is a rare condition where the kidney tissue dies due to a lack of blood supply, which can cause severe flank pain and could be considered in the differential diagnosis.
  • Pheochromocytoma: A rare tumor of the adrenal gland that can cause episodic pain and other symptoms, although it is less likely given the patient's presentation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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