Differential Diagnosis for Painful Sores in Mouth for Months
- Single most likely diagnosis
- Aphthous ulcers: These are the most common cause of recurrent, painful mouth sores, and can persist for months if not properly managed.
- Other Likely diagnoses
- Oral lichen planus: A chronic inflammatory condition that can cause painful sores and ulcers in the mouth.
- Oral candidiasis (thrush): A fungal infection that can cause white patches and painful sores in the mouth, especially in immunocompromised individuals.
- Traumatic ulcers: Sores caused by accidental bites, dental work, or other trauma to the mouth.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Oral cancer: Although less common, oral cancer can present as a persistent, painful sore in the mouth, and early detection is crucial for effective treatment.
- HIV/AIDS: Immunocompromised individuals with HIV/AIDS are more susceptible to opportunistic infections, such as oral candidiasis and Kaposi's sarcoma, which can cause painful sores in the mouth.
- Sjögren's syndrome: An autoimmune disorder that can cause dry mouth and increase the risk of oral infections and sores.
- Rare diagnoses
- Pemphigus vulgaris: A rare autoimmune disorder that can cause blistering sores in the mouth and on the skin.
- Behçet's disease: A rare condition that can cause recurrent, painful mouth sores, as well as other symptoms such as genital sores and eye inflammation.
- Erythema multiforme: A rare skin condition that can cause painful sores in the mouth, as well as other symptoms such as skin lesions and eye inflammation.