From the Research
Oral steroids are not recommended for treating lip swelling associated with angular cheilitis due to their potential to worsen infections and cause significant side effects. Angular cheilitis is typically caused by fungal or bacterial infections, nutritional deficiencies, or excessive moisture at the corners of the mouth, and is better managed with targeted treatments 1. For angular cheilitis, the recommended approach includes:
- Antifungal creams (like clotrimazole or nystatin) applied 2-3 times daily for 7-14 days if a fungal infection is suspected
- Antibacterial ointments (such as mupirocin) if bacterial infection is present
- Petroleum jelly to create a protective barrier while healing occurs Addressing underlying causes is essential, which may include:
- Improving oral hygiene
- Treating any dental issues that cause saliva pooling
- Correcting nutritional deficiencies (particularly B vitamins, iron, or zinc)
- Keeping the affected area clean and dry 2, 3. A study published in 2020 found that a combination of 1% isoconazole nitrate and 0.1% diflucortolone valerate ointment was effective in treating angular cheilitis, highlighting the importance of targeted treatment 1. Overall, oral steroids are not a recommended treatment option for angular cheilitis due to their potential risks and the availability of more effective and targeted treatments.