Can perimenopause cause skin rashes?

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Last updated: May 12, 2025 • View editorial policy

From the Guidelines

Perimenopause can cause rashes due to hormonal fluctuations, particularly the decline in estrogen levels, which can lead to skin changes including dryness, itchiness, and various types of rashes. The provided evidence does not directly address the relationship between perimenopause and rashes, but it discusses the hormonal changes during perimenopause and menopause, which can affect the skin. According to the example answer, declining estrogen levels can trigger or worsen conditions like eczema, contact dermatitis, or hives in some women 1. Some key points to consider when treating rashes associated with perimenopause include:

  • Using gentle, fragrance-free moisturizers daily
  • Taking lukewarm (not hot) showers
  • Using mild soaps
  • Applying over-the-counter hydrocortisone cream (0.5-1%) for temporary relief of itchy rashes
  • Considering prescription treatments, such as topical steroids or antihistamines like cetirizine (10mg daily), for persistent or severe rashes
  • In some cases, hormone replacement therapy may be necessary to address the underlying hormonal changes 2. It's essential to stay hydrated and avoid known skin irritants to manage rashes during perimenopause. Estrogen plays a significant role in maintaining skin moisture, thickness, and elasticity, so when levels decrease during perimenopause, the skin becomes more vulnerable to irritation and inflammation.

From the Research

Perimenopause and Rashes

  • There is no direct evidence in the provided studies that perimenopause can cause rashes 3, 4, 5, 6.
  • However, one study mentions that skin symptoms, including dryness and pruritus, can occur during menopause 7.
  • It is possible that the hormonal fluctuations during perimenopause may contribute to skin symptoms, but this is not explicitly stated in the provided studies.
  • The studies primarily focus on the management of perimenopausal and menopausal symptoms, such as vasomotor symptoms, mood fluctuations, and genitourinary symptoms, rather than skin symptoms like rashes 3, 4, 5, 6.
  • Hormone replacement therapy (HRT) is discussed as a treatment option for menopausal symptoms, but its potential effects on skin symptoms like rashes are not mentioned 4, 7, 6.

References

Research

Management of perimenopause disorders: hormonal treatment.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2021

Research

Hormone replacement therapy - Current recommendations.

Best practice & research. Clinical obstetrics & gynaecology, 2022

Research

The Menopause Transition: Signs, Symptoms, and Management Options.

The Journal of clinical endocrinology and metabolism, 2021

Research

Management of perimenopausal and menopausal symptoms.

BMJ (Clinical research ed.), 2023

Research

Skin, hair and beyond: the impact of menopause.

Climacteric : the journal of the International Menopause Society, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.