Can a patient undergoing chemotherapy (chemo) safely consume sushi?

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Last updated: May 13, 2025View editorial policy

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From the Guidelines

Chemotherapy patients should avoid eating sushi or other raw fish due to the high risk of foodborne illnesses associated with weakened immune systems. During chemotherapy, the immune system becomes compromised, making patients more susceptible to infections and illnesses caused by harmful bacteria, parasites, or other pathogens that may be present in raw fish 1. According to the American Cancer Society guide for informed choices, patients should avoid foods that may have potential bacterial contamination, such as sushi, raw or undercooked meat, fish, shellfish, poultry, and eggs 1.

Some key food safety guidelines for chemotherapy patients include:

  • Washing hands thoroughly before eating and food preparation
  • Keeping all aspects of food preparation clean, including washing fruits and vegetables thoroughly
  • Using special care in handling raw meats, fish, poultry, and eggs
  • Thoroughly cleaning all utensils, countertops, cutting boards, and sponges that have contacted raw meat
  • Cooking to proper temperatures, with meat, poultry, and seafood being thoroughly cooked, and beverages being pasteurized
  • Storing foods promptly at low temperatures to minimize bacterial growth

Instead of raw fish, chemotherapy patients can opt for fully cooked fish, which provides similar nutritional benefits without the risk. If you're craving sushi, consider vegetable sushi or rolls with cooked fish like eel (unagi) or shrimp tempura. It's essential to maintain good food hygiene practices and consult with your oncologist or a dietitian who specializes in cancer care for personalized dietary advice based on your specific treatment regimen and health status 1.

From the Research

Chemotherapy and Diet

  • There is no direct evidence in the provided studies 2, 3, 4 that discusses the safety of consuming sushi for chemotherapy patients.
  • The studies focus on the effects of chemotherapy agents, such as doxorubicin, oxaliplatin, cyclophosphamide, bortezomib, and paclitaxel, on tumor cells and the immune system.
  • They explore the molecular mechanisms underlying immunogenic cell death (ICD) and its potential application in cancer immunotherapy.

Food Safety and Chemotherapy

  • Chemotherapy patients often have compromised immune systems, making them more susceptible to foodborne illnesses.
  • However, the provided studies do not address specific dietary recommendations or restrictions for chemotherapy patients, including the consumption of sushi.
  • It is essential to consult with a healthcare professional or a registered dietitian for personalized dietary advice during chemotherapy treatment.

Immunogenic Cell Death and Chemotherapy

  • The studies 2, 3, 4 discuss the concept of immunogenic cell death (ICD) and its role in activating the immune system against tumor cells.
  • They investigate the combination of chemotherapy agents, such as cyclophosphamide and doxorubicin, to enhance anti-tumor immune activity.
  • While these studies provide valuable insights into the mechanisms of ICD and chemotherapy, they do not offer guidance on dietary choices for chemotherapy patients.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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