How should I write a prescription for Trelegy Ellipta (fluticasone furoate/umeclidinium bromide/vilanterol) on a prescription pad?

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Last updated: May 14, 2026 • View editorial policy

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How to Write a Prescription for Trelegy Ellipta

Write "Trelegy Ellipta" followed by the specific strength (100/62.5/25 mcg or 200/62.5/25 mcg), with directions for "one inhalation by mouth once daily" and dispense "1 inhaler (30 doses)" with appropriate refills.

Prescription Format

When writing for Trelegy Ellipta on a prescription pad, include these essential components:

Drug Name and Strength

  • Brand name: Trelegy Ellipta
  • Available strengths: 1
    • 100/62.5/25 mcg (fluticasone furoate/umeclidinium/vilanterol)
    • 200/62.5/25 mcg (fluticasone furoate/umeclidinium/vilanterol)

Complete Prescription Example

For COPD patients:

Trelegy Ellipta 100/62.5/25 mcg
Inhale one inhalation by mouth once daily
Disp: 1 inhaler (30 doses)
Refills: [as appropriate]

For patients requiring higher ICS dose:

Trelegy Ellipta 200/62.5/25 mcg
Inhale one inhalation by mouth once daily
Disp: 1 inhaler (30 doses)
Refills: [as appropriate]

Key Prescribing Details

Dosing Specifications

  • Frequency: Once daily only 1
  • Device: ELLIPTA dry powder inhaler 1
  • Supply: Each inhaler contains 30 doses (60 blisters total - 2 strips of 30 blisters each) 1
  • Discard date: 6 weeks after opening the foil tray 1

Important Prescribing Notes

Patient counseling points to document:

  • Rinse mouth with water after each use and spit out (do not swallow) 1
  • Not for acute symptoms or rescue use
  • Contains lactose monohydrate with milk proteins 1

Common pitfall: Do not prescribe as "PRN" or "as needed" - this is a maintenance medication requiring once-daily dosing for optimal efficacy 2.

Strength Selection Algorithm

Choose 100/62.5/25 mcg when:

  • Initiating triple therapy in most COPD patients
  • Switching from low-to-medium dose ICS/LABA combinations

Choose 200/62.5/25 mcg when:

  • Patient was previously on high-dose ICS combinations
  • Inadequate symptom control on lower ICS dose
  • Higher eosinophil counts or type 2 inflammation markers present 2

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.