Differential Diagnosis for Rash Involving Palms and Soles
- Single Most Likely Diagnosis
- Contact Dermatitis: This is a common condition that can cause a rash on the palms and soles due to exposure to irritants or allergens. The rash is typically itchy, red, and may blister.
- Other Likely Diagnoses
- Dyshidrotic Eczema: A type of eczema that primarily affects the palms and soles, characterized by small, itchy blisters.
- Psoriasis: A chronic skin condition that can cause red, scaly patches on the palms and soles.
- Palmoplantar Pustulosis: A rare skin condition characterized by pus-filled bumps on the palms and soles.
- Do Not Miss Diagnoses
- Secondary Syphilis: A systemic infection that can cause a rash on the palms and soles, often accompanied by other symptoms such as fever and lymphadenopathy. Missing this diagnosis can have serious consequences if left untreated.
- Hand-Foot-and-Mouth Disease: A viral infection that can cause a rash on the palms and soles, especially in children. While typically self-limiting, it can be severe in certain cases.
- Rare Diagnoses
- Keratoderma Blennorrhagicum: A rare skin condition associated with Reiter's syndrome, characterized by thickening of the skin on the palms and soles.
- Pityriasis Rubra Pilaris: A rare skin disorder that can cause a rash on the palms and soles, often accompanied by other skin lesions and systemic symptoms.