From the Guidelines
Furosemide (Lasix 40 mg) is the medication in this list that can lead to low magnesium levels, as it is a loop diuretic that can cause hypomagnesemia as a side effect, as stated in the study by 1. This medication works by increasing urine production, which can lead to the loss of magnesium and other essential electrolytes in the body.
- The study by 1 lists furosemide as a loop diuretic that can cause hypokalaemia, hypomagnesaemia, and hyponatraemia as major side effects.
- Another study by 1 also mentions that diuretics, including loop diuretics like furosemide, can cause electrolyte disturbances, including hypomagnesemia.
- Additionally, the study by 1 notes that hypomagnesemia can result from increased loss of magnesium from the kidneys, which can be caused by certain medications, including diuretics like furosemide. It is essential to monitor magnesium levels in patients taking furosemide, especially those with pre-existing magnesium deficiency or those taking other medications that can interact with magnesium levels.
- Symptoms of low magnesium can include muscle cramps, irregular heartbeat, fatigue, and neurological symptoms, as mentioned in the study by 1. Regular monitoring and potential magnesium supplementation can help prevent or manage hypomagnesemia in patients taking furosemide.
From the FDA Drug Label
Low magnesium levels In the body can happen in people who have taken lansoprazole delayed-release capsules for at least 3 months. To report any clinical symptoms that may be associated with hypomagnesemia to their healthcare provider, if they have been receiving lansoprazole delayed-release capsules for at least three months The medication that leads to low magnesium is lansoprazole 2, 2.
- Key points:
- Low magnesium levels can occur after taking lansoprazole for at least 3 months.
- Patients should report any symptoms of hypomagnesemia to their healthcare provider.
From the Research
Medications Leading to Low Magnesium
The following medications may lead to low magnesium levels:
- Lansoprazole (Prevacid 30 mg oral delayed release capsule) 3
- Furosemide (Lasix 40 mg oral tablet) 4, 5
- Proton pump inhibitors (PPIs), such as lansoprazole 3, 4
- Diuretics, such as furosemide 4, 5
Mechanisms of Low Magnesium
These medications can lead to low magnesium levels through various mechanisms, including:
- Increased renal magnesium loss (diuretics) 4, 5
- Impaired intestinal absorption of magnesium (PPIs) 3, 4
- Gastrointestinal loss of magnesium (chemotherapy, diarrhea) 6
Clinical Consequences of Low Magnesium
Low magnesium levels can have significant clinical consequences, including: