What is the most common allergen in Daktacort (miconazole + hydrocortisone) cream?

From the Guidelines

The most common allergen in Daktacort cream is actually miconazole nitrate, an antifungal component, but according to the provided evidence, the most common contact allergens include neomycin, however Daktacort does not contain neomycin, it contains miconazole nitrate and hydrocortisone. However, it's essential to note that Daktacort cream contains miconazole nitrate (an antifungal) and hydrocortisone (a steroid).

• Symptoms of an allergic reaction may include increased redness, itching, burning, or worsening of the skin condition being treated.
• If you experience these symptoms after applying Daktacort, you should discontinue use immediately and consult your healthcare provider.
• People with a known sensitivity to any of the components should avoid using this medication.
• Alternative antifungal preparations are available for those with known sensitivities.
• It's always advisable to perform a patch test on a small area of skin before applying the cream more widely, especially if you have a history of skin allergies or sensitivities to topical medications 1. Some of the common allergens that can cause allergic contact dermatitis include nickel, neomycin, fragrance, formaldehyde, and other preservatives, lanolin, and rubber chemicals 1. However, Daktacort cream's composition does not include neomycin, but rather miconazole nitrate and hydrocortisone, and the most common allergen in this specific cream would be related to its components, and miconazole nitrate is the antifungal component that could potentially cause an allergic reaction in sensitive individuals.

From the Research

Allergens in Daktacort Cream

• The most common allergen in Daktacort cream is not explicitly stated in the provided studies.
• However, according to 2, propylene glycol is a common cause of allergic contact dermatitis (ACD) and is an ingredient in some antifungal creams.
• Daktacort cream contains miconazole and hydrocortisone, but the studies do not specifically mention propylene glycol as an ingredient in Daktacort.
• Studies 3, 4, 5, and 6 discuss the efficacy and safety of Daktacort and its constituents, but do not provide information on the most common allergen in Daktacort cream.

Potential Allergens in Antifungal Creams

• 2 identifies six ingredients with frequent allergenic potential in antifungal creams, including propylene glycol.
• The study suggests that awareness of the allergenic potential of commonly used antifungal creams may help healthcare providers when evaluating patients with ACD.
• However, the study does not provide specific information on the allergenic potential of Daktacort cream or its ingredients.

Conclusion on Available Evidence

• There is no direct evidence in the provided studies to determine the most common allergen in Daktacort cream.
• Further research would be necessary to identify the most common allergen in Daktacort cream, as the available studies do not provide sufficient information on this topic 2, 3, 4, 5, 6.