What is the differential diagnosis for tender swollen papules on the hands?

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Differential Diagnosis for Tender Swollen Papules on Hands

The following differential diagnosis is organized into categories to help guide the thought process:

  • Single Most Likely Diagnosis
    • Dyshidrotic Eczema: This condition is characterized by tender, swollen papules on the hands, often accompanied by itching and burning sensations. It is a common condition that can be triggered by various factors, including stress, allergies, and environmental changes.
  • Other Likely Diagnoses
    • Contact Dermatitis: This is a type of skin inflammation caused by contact with irritants or allergens, resulting in tender, swollen papules on the hands.
    • Psoriasis: A chronic skin condition that can cause tender, swollen papules on the hands, often accompanied by scaling and redness.
    • Insect Bites or Stings: Reactions to insect bites or stings can cause tender, swollen papules on the hands.
  • Do Not Miss Diagnoses
    • Cellulitis: A bacterial skin infection that can cause tender, swollen papules on the hands, which can be serious if left untreated.
    • Erythema Multiforme: A skin condition that can be triggered by infections or medications, causing tender, swollen papules on the hands, and can be a sign of a more serious underlying condition.
    • Gout: A form of arthritis that can cause tender, swollen papules on the hands, especially if there is a history of joint pain or kidney stones.
  • Rare Diagnoses
    • Sarcoidosis: A condition that can cause tender, swollen papules on the hands, often accompanied by other systemic symptoms such as fever and fatigue.
    • Dermatomyositis: A rare autoimmune condition that can cause tender, swollen papules on the hands, often accompanied by muscle weakness and skin rash.
    • Keratoacanthoma: A rare skin condition that can cause tender, swollen papules on the hands, often resembling a small, dome-shaped tumor.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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