What is the cause of sudden, sharp pain in the medial aspect of the left ankle in a 7-year-old female, which worsens with running and walking, but persists at a level of 4/10 at rest, without discoloration or swelling?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Differential Diagnosis for a 7-year-old female with sudden sharp pain in the medial left ankle

  • Single most likely diagnosis:
    • Medial ankle sprain: This is the most likely diagnosis given the sudden onset of sharp pain in the medial ankle, worsened by running and walking, but still present at rest. The lack of discoloration and swelling suggests a mild sprain.
  • Other Likely diagnoses:
    • Growing pains: Although growing pains are typically bilateral and occur in the legs, they can sometimes be unilateral and localized to the ankle.
    • Overuse injury (e.g., medial ankle stress syndrome): Repetitive stress on the ankle from running or other activities can cause pain and inflammation in the medial ankle.
    • Ankle tendonitis (e.g., posterior tibialis tendonitis): Inflammation of the tendons surrounding the ankle can cause pain, especially with activity.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed):
    • Osteomyelitis: Although rare, osteomyelitis (bone infection) can cause severe pain, especially at night, and can be life-threatening if not treated promptly.
    • Septic arthritis: Bacterial infection of the joint can cause severe pain, swelling, and redness, and requires urgent medical attention.
    • Fracture (e.g., stress fracture or avulsion fracture): A fracture can cause sudden, severe pain, especially with weight-bearing activities.
  • Rare diagnoses:
    • Tumor (e.g., osteoid osteoma or Ewing's sarcoma): Although rare, bone tumors can cause persistent pain, especially at night, and should be considered in the differential diagnosis.
    • Inflammatory conditions (e.g., juvenile idiopathic arthritis): Chronic inflammatory conditions can cause joint pain, swelling, and stiffness, and may require specialized medical attention.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.