What is the diagnosis and treatment for a thyroglossal duct cyst?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 13, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Research

The most effective treatment for a thyroglossal duct cyst is surgical removal via the Sistrunk procedure, which involves removing the cyst, the central portion of the hyoid bone, and the tract leading to the base of the tongue, as evidenced by the low recurrence rate of 0.6% reported in the study by 1.

Key Points

  • Thyroglossal duct cysts are congenital neck masses that form from remnants of the thyroglossal duct, which normally disappears during fetal development.
  • These cysts typically present as a painless midline neck mass that moves upward when swallowing or sticking out the tongue.
  • The Sistrunk procedure is the recommended treatment for thyroglossal duct cysts, as it reduces the rate of recurrence from approximately 50 to 3-5% 2.
  • The procedure involves removing the cyst, the central portion of the hyoid bone, and the tract leading to the base of the tongue.
  • Antibiotics such as amoxicillin-clavulanate may be prescribed if the cyst becomes infected, but they are not a definitive treatment 3.
  • Surgery should be delayed until any infection resolves.
  • The Sistrunk procedure has been shown to be a safe and effective procedure, with a low recurrence rate and minimal complications 3, 1, 4.

Important Considerations

  • The type of resection is the most important factor related to recurrence, with the Sistrunk procedure being the most effective 1.
  • History of previous infection is also a significant predictor of postoperative recurrence 1.
  • Ultrasound imaging is a reliable and appropriate imaging modality for most patients with thyroglossal duct cysts 4.
  • Clinically diagnosed thyroglossal tract remnant may, in fact, be other pathologies in 10% of cases, highlighting the importance of thorough evaluation and diagnosis 4.

References

Research

A 16-year experience in treating thyroglossal duct cysts with a "conservative" Sistrunk approach.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2016

Research

Thyroglossal duct cyst excision.

Advances in oto-rhino-laryngology, 2012

Research

Sistrunk's operation for the treatment of thyroglossal cyst.

Mymensingh medical journal : MMJ, 2010

Research

The imperative of the Sistrunk operation: review of 160 thyroglossal tract remnant operations.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2009

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.