Differential Diagnosis for Penis Bump
- Single most likely diagnosis
- Genital wart (caused by Human Papillomavirus): This is a common condition that can cause bumps on the penis, often due to sexually transmitted infection.
- Other Likely diagnoses
- Fordyce spots: These are small, yellowish or white bumps on the penis that are caused by the presence of sebaceous glands and are usually harmless.
- Pearly penile papules: These are small, dome-shaped bumps that occur around the corona of the penis and are a normal anatomical variation.
- Herpes simplex virus (HSV) infection: This can cause painful bumps or blisters on the penis, often accompanied by other symptoms like itching, burning, or fever.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Penile cancer: Although rare, any unusual or persistent bump on the penis should be evaluated for the possibility of cancer, especially in older men or those with a history of HPV infection.
- Syphilis: This sexually transmitted infection can cause a variety of symptoms, including a painless bump or sore on the penis, and if left untreated, can lead to serious complications.
- Rare diagnoses
- Lichen planus: A chronic inflammatory condition that can cause bumps, itching, or burning on the penis, although this is less common.
- Psoriasis: This autoimmune condition can cause red, scaly patches or bumps on the penis, among other areas of the body.
- Keratoacanthoma: A rare, benign tumor that can appear as a bump on the penis, often resembling a small, dome-shaped nodule.