From the Research
Antibiotic eye drops or ointments containing erythromycin, bacitracin, or polymyxin B/trimethoprim are typically prescribed for styes that are infected or not responding to home treatment, as they are effective against Staphylococcus bacteria, the most common cause of styes 1. When considering treatment for a stye, it's essential to prioritize the most recent and highest quality evidence. The study published in 2025 in JAMA provides valuable insights into the management of Staphylococcus aureus bacteremia, which is relevant to the treatment of styes caused by this bacterium 1.
Key Considerations for Treatment
- Before starting antibiotics, warm compresses should be applied to the affected eye for 10-15 minutes, 3-4 times daily to help the stye drain naturally.
- Antibiotics become necessary when there's significant infection, spreading redness, or no improvement after 48 hours of home care.
- Never squeeze or pop a stye as this can spread the infection.
- If symptoms worsen despite treatment or you develop vision changes, fever, or severe pain, seek immediate medical attention.
Recommended Treatment Regimen
- Antibiotic eye drops or ointments containing erythromycin, bacitracin, or polymyxin B/trimethoprim are usually applied 3-4 times daily for 5-7 days.
- For more severe infections, oral antibiotics like dicloxacillin or cephalexin (250-500mg four times daily for 7-10 days) may be necessary. The choice of antibiotic should be guided by the most recent evidence and the specific needs of the patient, taking into account factors such as the severity of the infection and the potential for antibiotic resistance 2, 3, 4.