From the Guidelines
I strongly advise against taking 2 ER 30mg Adderall tablets at once, as this exceeds the recommended maximum daily dose and can lead to severe side effects. Taking too much Adderall can result in dangerous health consequences, including increased blood pressure and heart rate, potential seizures, extreme anxiety, and psychosis, as the medication contains amphetamine salts that stimulate the central nervous system 1. The maximum total daily dose of amphetamines, such as those found in Adderall, is generally recommended to be 40 mg, with some experts limiting the upper range to 25 mg for a single dose of MPH, when MPH is given in multiple doses throughout the day 1. Some key points to consider when taking stimulant medications like Adderall include:
- Starting with a low dose and gradually increasing as needed and under medical supervision
- Monitoring for side effects, such as insomnia, anorexia, headaches, social withdrawal, tics, and weight loss
- Regular follow-up appointments with a healthcare provider to assess the effectiveness of the medication and make any necessary adjustments If your current medication isn't effectively managing your symptoms, it's essential to consult your healthcare provider, who can evaluate your response and make appropriate adjustments to your treatment plan, which may include adjusting your dosage, changing medication timing, or trying a different medication altogether 1. Never adjust prescription medication dosages without medical supervision, as this can lead to serious health risks.
From the FDA Drug Label
OVERDOSAGE ... 30 mg can produce severe reactions The FDA drug label does not answer the question.
From the Research
Dosage and Administration
- The provided studies do not specifically address the question of taking 2 ER 30mg Adderalls 2, 3, 4, 5, 6.
- However, it is mentioned that the choice of drug and dosage can be tailored to patients' circumstances, especially intended duration of action, and then titrated week by week, according to response 3.
- Lisdexamfetamine, a type of amphetamine, is recommended as a first-choice medication for ADHD, and its dosage can range from 30 mg/d to 70 mg/d 2.
Efficacy and Safety
- Amphetamines, including lisdexamfetamine, have been shown to be efficacious in reducing the severity of ADHD symptoms in adults 2 and children/adolescents 4.
- However, amphetamines are associated with an increased proportion of patients who withdraw due to adverse events, such as decreased appetite, insomnia, abdominal pain, nausea/vomiting, headaches, and anxiety 2, 4.
- The quality of evidence for the efficacy and safety of amphetamines is generally low to very low due to the high risk of bias in the included studies 2, 4.
Pharmacology and Clinical Outcomes
- Different amphetamine compositions have varying pharmacological and pharmacokinetic effects, which can contribute to differences in clinical outcomes and abuse liability 5.
- Long-acting amphetamine compositions, such as lisdexamfetamine, have been shown to be efficacious without increased adverse effects and may have reduced abuse liability compared to short-acting amphetamine compositions 5.