What causes a metallic or salty taste in the mouth (hypogeusia)?

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Last updated: May 13, 2025View editorial policy

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Differential Diagnosis for SALTINESS IN MOUTH

  • Single most likely diagnosis
    • Dehydration: This is often the most common cause of a salty taste in the mouth, as the body concentrates the saliva, making it taste saltier.
  • Other Likely diagnoses
    • Medication side effects: Certain medications, such as antihistamines, decongestants, and blood pressure medications, can cause a salty taste in the mouth as a side effect.
    • Oral infections: Conditions like gum disease, tooth abscess, or oral thrush can lead to changes in taste, including a salty taste.
    • Hormonal changes: Hormonal fluctuations during pregnancy, menopause, or other endocrine disorders can affect taste, leading to a salty sensation.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Adrenal insufficiency: Although rare, adrenal insufficiency can cause changes in taste, including a salty taste, and is a life-threatening condition if not treated promptly.
    • Sjögren's syndrome: This autoimmune disorder can cause dry mouth and changes in taste, including a salty taste, and can be associated with other serious conditions.
  • Rare diagnoses
    • Taste disorders: Certain rare conditions, such as dysgeusia or hypogeusia, can cause abnormal tastes, including a salty taste.
    • Neurological disorders: Conditions like multiple sclerosis, Bell's palsy, or stroke can affect the nerves responsible for taste, leading to a salty taste.
    • Endocrine tumors: Rare tumors, such as a pheochromocytoma, can cause changes in taste, including a salty taste, due to hormonal imbalances.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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