Can Group B Streptococcus (GBS) urinary tract infection (UTI) cause glomerulonephritis?

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Last updated: February 19, 2025View editorial policy

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From the Research

Yes, a group B streptococcus (GBS) urinary tract infection (UTI) can potentially cause glomerulonephritis, although it is not a common occurrence. Glomerulonephritis is typically associated with group A streptococcal infections, but any severe bacterial infection, including a GBS UTI, could potentially lead to kidney complications in rare cases. The mechanism involves the body's immune response to the infection, which can sometimes affect the kidneys' filtering units (glomeruli) [ 1 ]. While the direct link between GBS UTIs and glomerulonephritis is not as well-established as with other types of infections, it's essential to monitor kidney function in patients with severe or persistent GBS UTIs [ 2, 3 ]. Some studies have reported cases of GBS UTIs, highlighting the emerging role of GBS in urinary tract infections [ 3 ]. However, the relationship between GBS UTIs and glomerulonephritis is not as well-studied as other types of infections, such as post-streptococcal glomerulonephritis (PSGN) [ 4 ]. In cases where glomerulonephritis is suspected, immediate medical attention is necessary, and treatment would typically involve addressing the underlying infection with appropriate antibiotics and managing any kidney-related symptoms or complications [ 1 ]. It is crucial to consider the possibility of glomerulonephritis in patients with severe or persistent GBS UTIs and to monitor their kidney function closely to prevent long-term kidney damage. Key points to consider include:

  • GBS UTIs can potentially cause glomerulonephritis in rare cases
  • Monitoring kidney function is essential in patients with severe or persistent GBS UTIs
  • Treatment involves addressing the underlying infection with appropriate antibiotics and managing kidney-related symptoms or complications
  • The relationship between GBS UTIs and glomerulonephritis is not as well-studied as other types of infections, but it is essential to consider the possibility of glomerulonephritis in patients with severe or persistent GBS UTIs.

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This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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