From the Guidelines
Yes, it is completely normal for one testicle to be larger than the other. In most men, the left testicle typically hangs lower than the right, while the right testicle is often slightly larger than the left [ 1 ]. This natural asymmetry is similar to how other paired body parts like feet, hands, or eyes may not be perfectly identical in size. The difference is usually subtle and not cause for concern. However, if you notice a sudden change in size, significant asymmetry, pain, swelling, or lumps, you should consult a healthcare provider promptly. These could indicate conditions requiring medical attention such as infection, injury, varicocele (enlarged veins), hydrocele (fluid collection), or rarely, tumors [ 1 ].
Key Points to Consider
- A physical examination is essential in evaluating testicular size and consistency [ 1 ]
- High-frequency testicular US can detect testicular masses and characterize the contralateral testicle [ 1 ]
- Becoming familiar with your normal anatomy through self-examinations can help recognize concerning changes that might need medical evaluation
- It is crucial to consult a healthcare provider if you notice any unusual changes or symptoms, as early detection and treatment can significantly impact morbidity, mortality, and quality of life [ 1 ]
Recommendations for Evaluation
- A thorough physical examination, including testicular size and consistency, should be performed [ 1 ]
- Imaging studies, such as high-frequency testicular US, may be necessary to confirm the presence of a testicular mass or evaluate testicular characteristics [ 1 ]
- A combination of physical examination, history, and semen analysis can provide valuable information in evaluating male infertility [ 1 ]
From the Research
Testicle Size Variation
- It is not uncommon for one testicle to be slightly larger than the other, but the provided study does not directly address this topic 2.
- The study focuses on the management of epididymo-orchitis, a condition characterized by inflammation of the epididymis and testicle, and does not provide information on normal testicle size variation 2.
- There are no research papers provided that specifically investigate the normal size variation between testicles, making it difficult to determine if a size difference is normal or not.
Relevant Information
- The study provides guidance on the diagnosis and treatment of epididymo-orchitis, including empirical treatment options and health promotion principles 2.
- It emphasizes the importance of starting empirical treatment in patients with objective swelling and tenderness on testicular examination 2.
- However, this information is not directly relevant to the question of testicle size variation.
Available Data
- There are no data provided in the study that would help answer the question of whether it is normal for one testicle to be bigger than the other 2.