From the FDA Drug Label
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested: ... : children under 6 years, 50 mg daily in divided doses As a sedative when used as a premedication and following general anesthesia: ... and 0. 6 mg/kg in children
- Infant dosing: The label provides dosing information for children under 6 years, which may include infants.
- Hydrazine dose in infants: 0.6 mg/kg can be used for sedation in children, which may be applicable to infants. However, for other indications, a fixed dose of 50 mg daily in divided doses is recommended for children under 6 years, which may not be suitable for all infants due to varying weights. 1
From the Research
Hydrazine is not a medication used in infants and is actually a highly toxic chemical compound primarily used as a rocket propellant and in industrial applications. It is not approved for medical use in infants or any human patients. If you are asking about a medication for infants, there may be confusion with a different drug name.
Key Points to Consider
- Hydralazine (not hydrazine) is a vasodilator sometimes used to treat hypertension in pediatric patients, including infants in certain circumstances.
- For hydralazine in infants, the typical dosing is 0.1-0.5 mg/kg/dose given every 6-8 hours, with careful blood pressure monitoring, as noted in general medical practice 2.
- Treatment should only be initiated by a pediatrician or neonatologist, as dosing must be individualized based on the infant's weight, age, kidney function, and blood pressure response.
- Side effects may include tachycardia, fluid retention, and feeding difficulties.
- Hydralazine works by directly relaxing arterial smooth muscle, leading to vasodilation and reduced blood pressure.
- Never administer any medication to an infant without specific medical direction from a qualified healthcare provider, emphasizing the importance of professional guidance in medical treatment 3, 4.
Relevant Considerations
- The provided studies do not directly address the use of hydrazine in infants but highlight its toxic nature and industrial applications 5, 6.
- The focus should always be on approved medications and treatments, with hydralazine being a relevant example for infant hypertension under medical supervision.