Differential Diagnosis for Lymphoma Symptoms
The symptoms of lymphoma can vary depending on the type and location of the cancer. Here's a differential diagnosis for lymphoma symptoms, categorized for clarity:
- Single Most Likely Diagnosis
- Hodgkin Lymphoma: This is one of the most common types of lymphoma, especially in young adults. Symptoms can include swollen lymph nodes, fever, night sweats, and weight loss.
- Other Likely Diagnoses
- Non-Hodgkin Lymphoma (NHL): NHL is more common than Hodgkin lymphoma and can cause a wide range of symptoms depending on the type and location of the tumor. Common symptoms include swollen lymph nodes, fever, and weight loss.
- Chronic Lymphocytic Leukemia (CLL): CLL is a type of cancer that affects the blood and bone marrow, causing symptoms such as swollen lymph nodes, fatigue, and recurrent infections.
- Infectious Mononucleosis: Caused by the Epstein-Barr virus, this infection can cause symptoms similar to lymphoma, including swollen lymph nodes, fever, and fatigue.
- Do Not Miss Diagnoses
- Lymphoma with Central Nervous System (CNS) Involvement: Lymphoma that spreads to the CNS can be life-threatening if not treated promptly. Symptoms can include confusion, seizures, and changes in vision or speech.
- Autoimmune Disorders (e.g., Rheumatoid Arthritis, Lupus): These conditions can cause symptoms similar to lymphoma, such as swollen lymph nodes and fatigue, and can be life-threatening if not properly managed.
- Tuberculosis or Other Chronic Infections: Chronic infections can cause symptoms similar to lymphoma, including fever, night sweats, and weight loss, and can be life-threatening if not treated.
- Rare Diagnoses
- Castleman Disease: A rare disorder that causes an overgrowth of cells in the lymph nodes, leading to symptoms such as fever, weight loss, and swollen lymph nodes.
- Lymphomatoid Granulomatosis: A rare condition that causes inflammation and damage to the lungs, skin, and other organs, leading to symptoms such as cough, shortness of breath, and skin lesions.
- Post-Transplant Lymphoproliferative Disorder (PTLD): A rare condition that occurs in people who have undergone organ transplants, causing symptoms such as swollen lymph nodes, fever, and weight loss.
Each of these diagnoses has a unique set of symptoms and characteristics, and a thorough medical evaluation is necessary to determine the underlying cause of the symptoms.