What is the recommended dosage of Medroxyprogesterone (MPA) for Deviry (Medroxyprogesterone acetate)?

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From the Guidelines

The recommended dosage for Deviry is not explicitly mentioned in the provided evidence, however, based on the context of hormonal replacement therapy, it can be inferred that Deviry might be related to a progestin, and the dosage of progestin can vary depending on the specific formulation and the patient's needs. For example, in the context of hormonal replacement therapy, the dose of medroxyprogesterone acetate (MPA) can range from 200 mg of oral (or vaginal) MPA for 12–14 every 28 days in sequential regimens 1. When considering the use of combined 17βE and progestin patches, the dosage of progestin such as levonorgestrel can vary depending on the specific product and the patient's needs 1. It is essential to consult a healthcare provider to determine the specific dosage of Deviry or any other medication, as the needs of each patient may vary based on individual factors such as medical history, age, and response to treatment. In general, the dosage of hormonal replacement therapy medications, including progestins, should be adjusted according to each woman's tolerance and feeling of wellbeing 1. The decision to start or continue hormonal replacement therapy, including the use of Deviry, should be made after careful consideration of the potential benefits and risks, and under the guidance of a qualified healthcare provider.

From the Research

Deviry Dosage Information

  • The provided studies do not specifically mention the term "Deviry" or its dosage.
  • However, the studies discuss the use of progestins, such as medroxyprogesterone acetate (MPA), in the treatment of endometriosis.
  • According to the study 2, oral medroxyprogesterone acetate (MPA) was given in a dosage of 30 mg daily for 90 days to treat endometriosis.
  • Another study 3 mentions the use of MPA at a dosage of 50 mg/d for 3 months to treat endometriosis.

Progestin Therapy in Endometriosis

  • Progestins are synthetic compounds that mimic the effects of progesterone and have been used to treat endometriosis for over 50 years 4.
  • Continuous progestin use is an effective therapy for the treatment of painful symptoms associated with endometriosis 4.
  • The studies suggest that progestins can be delivered in different formulations, including oral preparations, injections, subdermal implants, and intrauterine systems 5, 4.

Efficacy and Safety of Progestins

  • The studies indicate that progestins are effective in reducing or eliminating pain symptoms in approximately 90% of patients with endometriosis 4.
  • However, the studies also mention that progestins can have side effects, such as spotting and breakthrough bleeding 2, 3.
  • The efficacy and safety of progestins may vary depending on the specific progestin used, the dosage, and the individual patient 5, 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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