From the Research
Long-term use of Cremaffin is not recommended due to potential problems such as dependency, malabsorption of fat-soluble vitamins, and skin irritation. However, the provided evidence does not directly address the long-term usage problems of Cremaffin. The evidence provided focuses on the treatment of atopic dermatitis and the use of topical corticosteroids and immunomodulators. According to the most recent study 1, the treatment of atopic dermatitis involves the use of topical corticosteroids, pimecrolimus, and tacrolimus, as well as lifestyle modifications such as liberal use of emollients and daily bathing with soap-free cleansers. Some key points to consider when treating atopic dermatitis include:
- The use of topical corticosteroids as the first-line treatment for atopic dermatitis flare-ups 1
- The use of pimecrolimus and tacrolimus as topical calcineurin inhibitors that can be used in conjunction with topical corticosteroids as first-line treatment 1
- The importance of lifestyle modifications such as liberal use of emollients and daily bathing with soap-free cleansers 1 It is essential to prioritize the patient's quality of life and to consider the potential risks and benefits of long-term treatment. In the context of real-life clinical medicine, it is crucial to make decisions based on the most recent and highest-quality evidence available, while also considering the individual patient's needs and circumstances. Therefore, it is recommended to use Cremaffin for short periods (less than 1-2 weeks) to relieve occasional constipation, and to focus on lifestyle modifications and safer long-term management options for chronic constipation.