What are the effects of Wild Lettuce (Lactuca virosa)?

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Last updated: May 14, 2025View editorial policy

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From the Research

Wild lettuce (Lactuca virosa) should be avoided due to its potential toxic effects, as evidenced by a case report of eight patients with manifestations of wild lettuce toxicity 1. When considering the use of wild lettuce, it is essential to prioritize morbidity, mortality, and quality of life as outcomes. The potential risks associated with wild lettuce consumption, including toxic effects and allergic reactions, outweigh any potential benefits. Some key points to consider when evaluating the use of wild lettuce include:

  • The lack of FDA approval for medical use and thorough studies on its effects and safety
  • The potential for side effects such as drowsiness, dizziness, and allergic reactions
  • The risk of contamination with Angiostrongylus cantonensis, the causative agent of human rat lungworm disease, particularly in endemic areas 2
  • The importance of consulting with a healthcare provider before using wild lettuce, especially for individuals with existing health conditions or taking other medications. Given the potential risks and limited benefits, it is recommended to avoid consuming wild lettuce (Lactuca virosa) due to its potential toxic effects and other associated risks 1.

References

Research

Wild lettuce (Lactuca virosa) toxicity.

BMJ case reports, 2009

Research

The potential danger of eating wild lettuce: a brief review of human rat lungworm infection.

Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health, 2014

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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