What is the cause of a fine macular rash on the dorsum of the hand?

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Last updated: May 14, 2025View editorial policy

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Differential Diagnosis for Fine Macular Rash on the Dorsum of the Hand

  • Single most likely diagnosis
    • Contact dermatitis: This is a common condition that occurs when the skin comes into contact with an irritant or allergen, leading to a rash. The dorsum of the hand is a common site for contact dermatitis due to exposure to various substances.
  • Other Likely diagnoses
    • Eczema (atopic dermatitis): A chronic skin condition characterized by dry, itchy, and inflamed skin. The hands can be affected, especially in individuals with a history of atopic dermatitis.
    • Psoriasis: An autoimmune condition that can cause a rash on various parts of the body, including the hands. The rash is often accompanied by scaling and thickening of the skin.
    • Tinea manuum: A fungal infection of the hand, which can cause a macular rash on the dorsum of the hand.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
    • Lyme disease: A bacterial infection transmitted by tick bites, which can cause a distinctive rash (erythema migrans) on the skin. Although less common, it's crucial to consider Lyme disease due to its potential severity if left untreated.
    • Rocky Mountain spotted fever: A bacterial infection transmitted by tick bites, which can cause a rash on the hands and feet. This condition can be life-threatening if not promptly treated.
  • Rare diagnoses
    • Pityriasis rosea: A rare skin condition characterized by a macular rash, often accompanied by a "herald patch" on the trunk. Although less common, it can affect the hands.
    • Secondary syphilis: A bacterial infection that can cause a macular rash on various parts of the body, including the hands. This condition is relatively rare but important to consider due to its potential consequences if left untreated.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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