From the Guidelines
Feeling hot is a common side effect of prednisone, and it can be managed by staying in cooler environments, wearing lightweight clothing, and staying well-hydrated 1. This occurs because prednisone, a corticosteroid medication, can affect your body's temperature regulation mechanisms. The medication can increase your metabolic rate and alter blood vessel dilation, which may cause you to feel warmer than usual. To manage this sensation, you can try:
- Staying in cooler environments
- Wearing lightweight clothing
- Using fans or air conditioning
- Staying well-hydrated
- Avoiding hot beverages, spicy foods, and alcohol If you're taking prednisone as prescribed and this side effect becomes bothersome, don't stop the medication abruptly, as this can be dangerous. Instead, consult your healthcare provider, who might adjust your dosage or recommend taking the medication at a different time of day. The hot sensation typically subsides once your body adjusts to the medication or after you complete your prescribed course of treatment. It's also important to note that long-term use of prednisone can lead to more severe side effects, such as osteoporosis, hypertension, and diabetes, which should be closely monitored by your healthcare provider 1. Regular monitoring for potential corticosteroid side effects, including hypertension, hyperglycemia, and osteoporosis, is crucial to minimize the risk of complications 1.
From the FDA Drug Label
Dermatologic acne, acneiform eruptions, allergic dermatitis, alopecia, angioedema, angioneurotic edema, atrophy and thinning of skin, dry scaly skin, ecchymoses and petechiae (bruising), erythema, facial edema, hirsutism, impaired wound healing, increased sweating, Karposi’s sarcoma (see PRECAUTIONS: General Precautions), lupus erythematosus-like lesions, perineal irritation, purpura, rash, striae, subcutaneous fat atrophy, suppression of reactions to skin tests, striae, telangiectasis, thin fragile skin, thinning scalp hair, urticaria
The side effect of feeling hot is not directly mentioned in the drug label, but increased sweating is listed as a possible adverse reaction. This could be related to feeling hot, but it is not a direct answer to the question. 2
From the Research
Side Effects of Prednisone
- Feeling hot is not a commonly reported side effect of prednisone in the provided studies 3, 4, 5, 6, 7
Related Side Effects
- Digestive disturbances, such as indigestion and heartburn, are common side effects of prednisone, but can be reduced with the use of antacids 5
- Long-term use of prednisone can lead to osteoporosis, particularly in patients who do not receive preventive treatment 4, 6
- Other side effects of prednisone may include weight gain, mood changes, and increased risk of fractures 3, 6, 7