What are the differential diagnoses for Deep Vein Thrombosis (DVT)?

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Last updated: February 20, 2025 • View editorial policy

Differential Diagnosis for DVT

  • Single Most Likely Diagnosis + Deep Vein Thrombosis (DVT): This is the most likely diagnosis given the presentation, as DVT is a common condition that can cause symptoms such as leg swelling, pain, and warmth.
  • Other Likely Diagnoses + Cellulitis: An infection of the skin and subcutaneous tissue that can cause similar symptoms to DVT, such as redness, swelling, and warmth. + Musculoskeletal injury: A muscle or tendon injury can cause pain and swelling in the affected leg, mimicking DVT symptoms. + Lymphedema: A condition characterized by chronic swelling of the leg due to impaired lymphatic drainage, which can be mistaken for DVT.
  • Do Not Miss Diagnoses + Pulmonary Embolism (PE): A potentially life-threatening condition that can occur if a DVT breaks loose and travels to the lungs, making it crucial to consider and rule out. + Phlegmasia Cerulea Dolens: A rare but severe condition caused by extensive DVT, leading to limb ischemia and potentially gangrene. + Compartment Syndrome: A condition characterized by increased pressure within a muscle compartment, which can cause severe pain, swelling, and potentially permanent damage if not promptly treated.
  • Rare Diagnoses + Popliteal Artery Aneurysm: A rare condition where the popliteal artery becomes dilated, potentially causing leg swelling and pain. + Cystic Adventitial Disease: A rare condition characterized by the formation of cysts within the adventitia of the popliteal artery, leading to leg pain and swelling. + Thoracic Outlet Syndrome: A rare condition where the nerves and/or blood vessels between the neck and shoulder become compressed, potentially causing arm and leg symptoms.

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