From the Guidelines
Betahistine is recommended for pediatric use at a dosage of 7.5–10 mg/kg once a day (oral) 1. When considering the use of betahistine in children, it is essential to weigh the potential benefits against the risks, given the limited data available on its safety and efficacy in the pediatric population.
- The dosage of 7.5–10 mg/kg once a day (oral) is specified for children in the British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD) 1.
- This guideline provides the most recent and relevant information on the use of betahistine in pediatric patients, and its recommendations should be followed in clinical practice.
- It is crucial to note that betahistine is not typically used to treat the same conditions in children as it is in adults, and its use in pediatric patients should be carefully considered and monitored by a qualified healthcare professional.
- In the absence of more specific guidelines, the dosage recommended by the British Thoracic Society 1 should be used as a reference point for pediatric patients.
From the FDA Drug Label
Pediatric Use Histamine solutions for percutaneous testing have been given safely in infants and young children. Neonates and infants have lower skin test reactivity to histamines as well as common allergens. About 20% of infants less than six months of age have been observed to have a negative reaction to histamine hydrochloride (1 mg/mL of salt). The FDA drug label does not answer the question about Beta histine pediatric dosage for Betahistine (PO) as it discusses histamine solutions for percutaneous testing, not Betahistine (PO) dosage. 2
From the Research
Beta Histine Pediatric Dosage
- There is no specific information available in the provided studies regarding the pediatric dosage of beta histine.
- The studies primarily focus on the use of betahistine in adults for the treatment of vestibular disorders, such as Meniere's disease, benign paroxysmal positional vertigo, and vestibular neuronitis 3, 4, 5, 6, 7.
- The dosage of betahistine mentioned in the studies ranges from 8-48 mg daily, with 48 mg daily for 3 months being an effective and safe option for the treatment of peripheral vertigo in adults 3, 5.
- However, there is no information available on the appropriate dosage for pediatric patients, and further research would be needed to determine the safety and efficacy of betahistine in children.