What causes lower rib pain?

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Last updated: May 15, 2025View editorial policy

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Differential Diagnosis for Lower Rib Pain

  • Single most likely diagnosis
    • Musculoskeletal strain: This is the most common cause of lower rib pain, often resulting from overuse, trauma, or poor posture. The pain is typically sharp and worsens with movement or deep breathing.
  • Other Likely diagnoses
    • Costochondritis: Inflammation of the cartilage that connects the ribs to the sternum, causing sharp pains in the chest and rib area.
    • Precordial catch syndrome: A benign condition characterized by sudden, sharp pains in the chest and rib area, often triggered by deep breathing or movement.
    • Gastroesophageal reflux disease (GERD): Stomach acid reflux can cause pain in the lower chest and rib area, especially after eating or at night.
    • Pulmonary embolism (less common, but important to consider): A blood clot in the lungs can cause sudden, severe chest pain, including lower rib pain.
  • Do Not Miss (ddxs that may not be likely, but would be deadly if missed)
    • Pneumonia: Infection in the lungs can cause lower rib pain, especially if the infection is located in the lower lobes.
    • Pulmonary embolism: As mentioned earlier, a blood clot in the lungs can be life-threatening and requires immediate medical attention.
    • Cardiac ischemia or myocardial infarction: Although less common, cardiac conditions can cause referred pain in the lower rib area.
    • Sickle cell crisis: Individuals with sickle cell disease can experience severe pain episodes, including lower rib pain, due to vaso-occlusive crises.
  • Rare diagnoses
    • Tietze's syndrome: A rare condition characterized by inflammation of the cartilage in the chest, causing pain and swelling in the rib area.
    • Spondyloarthritis: A group of inflammatory diseases that can cause pain and stiffness in the spine, ribs, and other joints.
    • Osteoporotic rib fracture: Weakened bones can increase the risk of rib fractures, which can cause lower rib pain.
    • Thoracic spine fracture or herniated disk: Trauma or degenerative changes in the thoracic spine can cause lower rib pain due to referred pain or nerve compression.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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