What are the recommendations for preventing candidiasis (yeast infection)?

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Last updated: May 15, 2025View editorial policy

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From the Guidelines

To prevent yeast infections, it is recommended to maintain good hygiene and consider preventive measures such as fluconazole (150mg weekly for 6 months) for those prone to recurrent infections, as supported by high-quality evidence 1. When it comes to preventing yeast infections, several strategies can be employed. These include:

  • Maintaining good hygiene by keeping the genital area clean and dry
  • Wiping from front to back after using the toilet to prevent bacterial transfer
  • Avoiding douches or scented feminine products that can disrupt vaginal pH
  • Wearing loose-fitting, cotton underwear and avoiding staying in wet clothing like swimsuits or workout clothes for extended periods
  • Dietary changes, such as limiting sugar and refined carbohydrates, while consuming probiotics found in yogurt with live cultures or supplements containing Lactobacillus
  • Considering probiotics simultaneously when taking antibiotics, which can kill beneficial bacteria and allow yeast to overgrow For those prone to recurrent infections, preventive measures may include:
  • Boric acid suppositories (600mg inserted vaginally at bedtime for 7-14 days)
  • Maintenance doses of antifungal medications like fluconazole (150mg weekly for 6 months) under medical supervision, as recommended by the Infectious Diseases Society of America 1 These strategies work by maintaining the vagina's natural acidic environment and healthy bacterial balance, which helps prevent Candida yeast from overgrowing and causing infection. It is essential to note that the use of fluconazole for prevention is supported by strong recommendation and high-quality evidence 1, making it a preferred option for those at high risk of recurrent yeast infections.

From the Research

Yeast Infection Prevention Recommendations

To prevent yeast infections, several strategies can be employed, including:

  • Using probiotics, such as Lactobacillus acidophilus, to maintain a healthy vaginal microbiota 2, 3, 4
  • Consuming lactoferrin, which has been shown to have antimicrobial properties and enhance the effectiveness of probiotics 5, 2
  • Avoiding unnecessary antibiotic use, which can disrupt the balance of vaginal microflora 5
  • Considering fluconazole prophylaxis for women with recurrent vulvovaginal candidiasis (RVVC), although concerns about resistance and overuse should be taken into account 4, 6

Non-Pharmacological Interventions

Non-pharmacological interventions, such as:

  • Using Redcore lotion in combination with miconazole, have shown promise in reducing episodes of VVC 4
  • Probiotic consumption has been associated with a decreased rate of recurrence 4

Pharmacological Interventions

Pharmacological interventions, including:

  • Fluconazole, ketoconazole, clotrimazole, and oteseconazole, have been shown to be effective in reducing the risk of mycological recurrence 4
  • Azoles and antibiotics can also be considered viable options for treating VVC, although more studies are needed to determine their effectiveness in specific conditions, such as pregnancy or immunodeficiency 4

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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