Differential Diagnosis for Thy3f on Final Histology
Single most likely diagnosis
- Papillary thyroid carcinoma: This is the most common type of thyroid cancer, and a Thy3f (follicular variant of papillary thyroid carcinoma) on final histology is consistent with this diagnosis. The follicular variant of papillary thyroid carcinoma is a subtype of papillary thyroid carcinoma that can be challenging to diagnose preoperatively.
Other Likely diagnoses
- Follicular thyroid carcinoma: Although less likely than papillary thyroid carcinoma, follicular thyroid carcinoma can also present with a Thy3f on final histology, especially if there are areas of follicular architecture and capsular or vascular invasion.
- Hurthle cell carcinoma: This is a rare type of thyroid cancer that can also present with a Thy3f on final histology, especially if there are areas of Hurthle cell differentiation.
Do Not Miss diagnoses
- Medullary thyroid carcinoma: Although less common, medullary thyroid carcinoma can present with a Thy3f on final histology, especially if there are areas of spindle cell or squamous differentiation. Missing this diagnosis can have significant implications for treatment and prognosis.
- Anaplastic thyroid carcinoma: This is a rare and aggressive type of thyroid cancer that can present with a Thy3f on final histology, especially if there are areas of anaplastic or undifferentiated carcinoma. Missing this diagnosis can have devastating consequences.
Rare diagnoses
- Poorly differentiated thyroid carcinoma: This is a rare type of thyroid cancer that can present with a Thy3f on final histology, especially if there are areas of solid or trabecular growth and high mitotic activity.
- Thyroid lymphoma: This is a rare type of thyroid cancer that can present with a Thy3f on final histology, especially if there are areas of lymphoid infiltration and destruction of thyroid tissue.