What are four non-surgical complications of anti-reflux (Gastroesophageal Reflux Disease) surgery?

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Last updated: May 15, 2025View editorial policy

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From the Guidelines

Four non-surgical complications of anti-reflux surgery include dysphagia, gas-bloat syndrome, diarrhea, and recurrence of reflux symptoms. These complications can significantly impact a patient's quality of life and morbidity, and it is essential to consider them when deciding on the best course of treatment for gastroesophageal reflux disease (GERD) 1.

Non-Surgical Complications

  • Dysphagia (difficulty swallowing) is a common complication, affecting up to 6% of patients undergoing antireflux surgery, as reported in the american gastroenterological association medical position statement on the management of gastroesophageal reflux disease 1.
  • Gas-bloat syndrome occurs when patients are unable to belch normally after surgery, leading to abdominal bloating, discomfort, and excessive flatulence, which can be debilitating for some patients 1.
  • Diarrhea may develop in some patients due to altered vagal nerve function affecting gut motility or from bile salt malabsorption, highlighting the need for careful patient selection and counseling before undergoing anti-reflux surgery 1.
  • Recurrence of reflux symptoms happens in approximately 10-15% of patients within 5 years, often due to anatomical failure of the surgical repair or adaptation of the gastroesophageal junction over time, emphasizing the importance of long-term follow-up and management 1.

Management and Counseling

Patients should be counseled about these potential complications before undergoing anti-reflux surgery to set appropriate expectations about post-operative recovery. Management of these complications may involve dietary modifications, medications like prokinetics for dysphagia, simethicone for gas symptoms, or loperamide for diarrhea. By carefully considering the potential benefits and risks of anti-reflux surgery, healthcare providers can help patients make informed decisions about their treatment and improve their overall quality of life 1.

From the Research

Non-Surgical Complications of Anti-Reflux Surgery

The following are four non-surgical complications that can occur after anti-reflux surgery:

  • Dysphagia: difficulty swallowing, which can be caused by a tight repair or vagal nerve injury 2, 3
  • Diarrhea: a common symptom after anti-reflux surgery, which can be caused by vagal nerve injury or other factors 2, 3
  • Gas bloat syndrome: a condition characterized by bloating, discomfort, and gas after eating, which can be caused by the surgery itself or other factors 2, 3
  • Vitamin B12 deficiency: a potential complication of anti-reflux surgery, particularly in patients who have had gastric or small intestine resections, or those who are taking certain medications such as proton pump inhibitors 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Evaluation and management of patients with symptoms after anti-reflux surgery.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2015

Research

Vitamin B12 Deficiency: Recognition and Management.

American family physician, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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