What are the differential diagnoses for atraumatic sacral pain, also known as sacralgia (sacral pain)?

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Differential Diagnosis for Atraumatic Sacral Pain

The differential diagnosis for atraumatic sacral pain can be organized into the following categories:

  • Single Most Likely Diagnosis
    • Sacroiliitis: This is often the most common cause of atraumatic sacral pain, especially in younger individuals. It can be due to inflammatory conditions such as ankylosing spondylitis or reactive arthritis.
  • Other Likely Diagnoses
    • Sacral stress fracture: Although more common in athletes or individuals with osteoporosis, stress fractures can occur in anyone and cause significant sacral pain.
    • Piriformis syndrome: This condition, where the piriformis muscle irritates the sciatic nerve, can cause sacral and buttock pain.
    • Coccydynia: Pain in the coccyx (tailbone) area can sometimes be perceived as sacral pain, especially if the pain radiates.
  • Do Not Miss Diagnoses
    • Cauda equina syndrome: A serious condition where the nerves in the spinal canal are compressed, leading to severe pain, numbness, and potentially permanent nerve damage if not promptly treated.
    • Spinal infection (e.g., osteomyelitis, discitis): Infections of the spine can cause severe pain and have serious consequences if not treated promptly.
    • Sacral insufficiency fracture with malignancy: Although rare, sacral pain could be the first sign of a malignancy, especially in older adults or those with a history of cancer.
  • Rare Diagnoses
    • Tarlov cysts: These are rare, fluid-filled cysts that can form on the nerve roots in the sacrum, causing pain and other neurological symptoms.
    • Sacral osteonecrosis: A rare condition where the bone tissue in the sacrum dies due to lack of blood supply, leading to pain and potentially collapse of the bone structure.
    • Intradural sacral meningeal cysts: These are rare, fluid-filled cysts that can compress nerves and cause pain, numbness, and other neurological symptoms.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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