What is the differential diagnosis of bilateral chest wall hyperesthesia (increased sensitivity)?

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Differential Diagnosis for Bilateral Chest Wall Hyperesthesia

Single Most Likely Diagnosis

  • Shingles (Herpes Zoster): This is a common condition that can cause hyperesthesia, especially if the patient has a history of herpes zoster infection. The pain and sensitivity can precede the rash, making it a likely diagnosis for bilateral chest wall hyperesthesia.

Other Likely Diagnoses

  • Costochondritis: Inflammation of the cartilage that connects the ribs to the breastbone can cause pain and hyperesthesia in the chest wall.
  • Musculoskeletal strain: Overuse or injury to the muscles and tendons in the chest wall can lead to hyperesthesia and pain.
  • Fibromyalgia: A chronic condition characterized by widespread muscle pain and tender points, which can include the chest wall.
  • Anxiety or stress: Can cause or exacerbate hyperesthesia and other sensory symptoms in the chest wall.

Do Not Miss Diagnoses

  • Myocardial infarction: Although less likely to cause bilateral hyperesthesia, it is a life-threatening condition that should not be missed. Some patients may experience referred pain or hyperesthesia in the chest wall during a heart attack.
  • Pulmonary embolism: Another life-threatening condition that can cause sudden onset of chest pain and hyperesthesia, especially if the embolism is large or involves multiple lung segments.
  • Pneumothorax: A collapsed lung can cause sudden onset of chest pain and hyperesthesia, especially if the pneumothorax is large or under tension.

Rare Diagnoses

  • Sjögren's syndrome: An autoimmune disorder that can cause neuropathic pain and hyperesthesia in various parts of the body, including the chest wall.
  • Multiple sclerosis: A chronic autoimmune disorder that can cause a wide range of neurological symptoms, including hyperesthesia and pain in the chest wall.
  • Neoplastic conditions: Rarely, tumors such as lymphoma or metastatic cancer can cause hyperesthesia and pain in the chest wall.
  • Peripheral neuropathy: Certain types of peripheral neuropathy, such as diabetic neuropathy or neuropathy due to vitamin deficiencies, can cause hyperesthesia and pain in the chest wall.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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