Is Ativan (lorazepam) contraindicated with fluoxetine?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: May 16, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

Ativan (lorazepam) is not contraindicated with most medications, but caution is advised when combining it with certain substances, including illicit drugs like "fucks" is not a medical term, however, assuming the question is about contraindications with recreational or illicit substances in general. When considering the use of Ativan with other substances, it's crucial to prioritize the patient's safety and well-being. The provided evidence does not directly address the term "fucks," but it discusses the importance of caution when combining medications, especially those that may interact with each other or exacerbate side effects 1.

Key Considerations

  • Ativan is a benzodiazepine that can enhance the effects of GABA, an inhibitory neurotransmitter, and is used for anxiety disorders.
  • Combining Ativan with other central nervous system depressants, including alcohol or illicit substances, can increase the risk of adverse effects such as sedation, drowsiness, dizziness, or impaired coordination.
  • The evidence emphasizes the need for caution when prescribing medications, especially in children and adolescents, due to the potential for increased risk of suicidal thinking and behavior, behavioral activation/agitation, and other adverse effects 1.
  • It is essential to start with lower doses and monitor patients closely when combining medications or substances that may interact with each other.
  • Patients should be educated about the potential risks and benefits of medication combinations and the importance of avoiding activities that require mental alertness until they know how the combination affects them.
  • Always inform healthcare providers about all medications and substances being taken to monitor for potential interactions and ensure safe treatment.

From the Research

Ativan Contraindications

  • There is no direct evidence in the provided studies regarding Ativan contraindications with other specific medications or substances, including "fucks" which is not a clear medical term.
  • However, it is known that Ativan (lorazepam) is a benzodiazepine, and benzodiazepines can have interactions with other substances, including medications and alcohol 2, 3.
  • The studies provided focus on the efficacy of various medications, including benzodiazepines, SSRIs, and other drugs, in treating anxiety disorders, bipolar depression, and obsessive-compulsive disorder 4, 5, 6.
  • It is essential to consult a healthcare professional for specific guidance on medication interactions and contraindications, as they can provide personalized advice based on individual circumstances.

Medication Interactions

  • Benzodiazepines, such as lorazepam, can have additive effects when combined with other central nervous system depressants, including alcohol and other medications 3.
  • SSRIs, which are commonly used to treat anxiety and depression, can interact with benzodiazepines, but the studies provided do not specifically address the interaction between Ativan and other substances 2, 5, 6.
  • The studies suggest that benzodiazepines can be effective in treating anxiety disorders, but they also highlight the potential for dependence and addictive effects 2, 3.

Conclusion Not Applicable

As per the instructions, a conclusion section is not provided. The information above is based on the available evidence and should not be considered as personalized advice. It is crucial to consult a healthcare professional for specific guidance on medication interactions and contraindications.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.