From the Research
Oral collagen supplements may provide modest benefits for bone health, though they are not a primary treatment for bone conditions, and should be considered as an adjunct to established therapies such as bisphosphonates and denosumab, as supported by recent studies 1. When considering the benefits of oral collagen for bone health, it is essential to prioritize established therapies that have a stronger evidence base for reducing morbidity, mortality, and improving quality of life.
- The most recent and highest quality study on osteoporosis treatment, published in 2025, highlights the importance of sequential and long-term therapy for osteoporosis, emphasizing the need for a comprehensive treatment plan that may include oral collagen supplements as an adjunct therapy 1.
- While oral collagen supplements may have some benefits, they should not be relied upon as the sole treatment for bone conditions, and patients should consult healthcare providers for personalized treatment plans that may include prescription medications such as bisphosphonates and denosumab, as recommended by studies published in 2021 and 2023 2, 3.
- The effectiveness of oral collagen supplements can be enhanced when combined with adequate calcium and vitamin D intake, as well as regular weight-bearing exercise, as suggested by a study published in 2017 4.
- It is crucial to note that the effectiveness of oral collagen supplements varies among individuals, and results typically take several months to become noticeable, emphasizing the need for patience and ongoing monitoring.
- In terms of cost-effectiveness, denosumab has been shown to be a cost-effective treatment strategy, especially among higher-risk and older adults with osteoporosis, as demonstrated by a study published in 2018 5.