From the FDA Drug Label
The FDA drug label does not answer the question.
From the Research
While there isn't a universally prescribed diet specifically for GLP-1 medication users, I recommend focusing on a balanced, nutrient-dense eating pattern that complements these medications' effects, as supported by the most recent study 1. GLP-1 agonists like semaglutide, liraglutide, and tirzepatide work by slowing gastric emptying and increasing satiety, so smaller, protein-rich meals are typically better tolerated. Some key points to consider when creating a diet for GLP-1 users include:
- Prioritizing lean proteins (chicken, fish, legumes), non-starchy vegetables, healthy fats (avocado, olive oil, nuts), and complex carbohydrates (whole grains, sweet potatoes)
- Limiting simple sugars and highly processed foods, as suggested by the mechanisms of action of GLP-1 agonists 2
- Staying well-hydrated with water and maintaining consistent meal timing to help manage potential side effects like nausea, which is a common side effect of GLP-1 agonists 3
- Ensuring nutritional adequacy to prevent muscle loss during weight reduction, as GLP-1 agonists can lead to weight loss 4 This approach supports the medication's effectiveness by preventing blood sugar spikes, maximizing satiety signals, and ensuring proper nutrition during periods of reduced caloric intake. It is also important to note that GLP-1 receptor agonists have been shown to have a low risk of hypoglycemia and can be effective in reducing A1C and weight, as demonstrated in head-to-head clinical studies 1. Overall, a balanced and nutrient-dense diet can help maximize the benefits of GLP-1 medications while minimizing potential side effects.