Differential Diagnosis for Rapidly Spreading Skin Infection
- Single most likely diagnosis
- Group A Strep: This is the most likely cause of a rapidly spreading skin infection with no evidence of a break in the skin or wound. Group A streptococcal infections can cause necrotizing fasciitis and streptococcal toxic shock syndrome, which are characterized by rapid progression and severe symptoms, even in the absence of an apparent entry point for the bacteria.
- Other Likely diagnoses
- Staph Aureus: While Staph aureus can cause skin infections, it is less likely to cause a rapidly spreading infection without an apparent break in the skin. However, Staph aureus can cause severe infections, including necrotizing fasciitis, especially in immunocompromised individuals or those with underlying medical conditions.
- Do Not Miss (ddxs that may not be likely, but would be deadly if missed.)
- Vibrio vulnificus: This bacterium can cause severe and rapidly progressing skin infections, especially in individuals with exposure to contaminated water or shellfish. Although less common, Vibrio vulnificus infections can be deadly if not promptly treated.
- Clostridium perfringens: This bacterium can cause gas gangrene, a severe and potentially life-threatening infection that can progress rapidly. While it typically requires a break in the skin, it is essential to consider this diagnosis in cases of rapidly spreading skin infections.
- Rare diagnoses
- Streptococcus pneumoniae: This bacterium can cause skin infections, including necrotizing fasciitis, although it is a rare cause of such infections.
- Haemophilus influenzae: This bacterium can cause skin infections, especially in immunocompromised individuals or those with underlying medical conditions, although it is a rare cause of rapidly spreading skin infections.
- Anaerobic bacteria: Various anaerobic bacteria can cause skin infections, including necrotizing fasciitis, although these are relatively rare and often require a break in the skin or underlying tissue damage.